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3-Methylaminopiperidine dihydrochloride

Oloa igoa:

3- (Methylamino) piperidine Dihydrochloride;

N-methylpiperidin-3-amine, dihydrochloride;

3- (Methylamino) piperidine dihydrochloride;

N-Methylpiperidin-3-amine dihydrochloride;

3-Methylaminopiperidine dihydrochloride;


Oloa Features

1.Cas Nu: 127294-77-3
2.Molecular fua faatatau: C6H16Cl2N2
Fausaga 3.Chemical

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4.Meli laina: 199-200 ° C
5. Vaʻaigofie: 253.7ºC
6. Fale teu oloa: Faleoloa i se malulu, mago nofoaga.

Talosaga: O se taua taua ogatotonu mo le tuʻufaʻatasia o fluoroquinolone vailaʻau faʻatamaʻi balofloxacin.

Folasaga:3-methylaminopiperidine (1) o se taua ogatotonu mo le tuʻufaʻatasia o fluoroquinolone vailaʻau vailaʻau balofloxacin. O tusitusiga e faʻaaogaina le γ-butyrolactone o ni mea masani ma oʻo i le amination, hydrolysis, esterification, ma le bromineO le Ethyl acetate condencies, cyclization, ester hydrolysis ma le decarboxylation, reductive amination ma le hydrogenolysis debenzyl na maua ai le 3-methylaminopiperidine, o laʻasaga o le Chemicalbook e umi, ma o le aofaʻi o fua e maualalo (na o le 11.5%). Faʻaaoga le 3-aminopyridine (2) e maua ai le 3-methylaminopyridine (4) e le formylation ma faʻaititia ma lithium alumini hydride; pe faʻapipiʻi i le 2 ma le triethyl orthoformate ma faʻaititia ma le sodium borioxidide e maua ai le 4,4. Faʻaititia o Pd / C e sauniuni ai le 3-methylaminopiperidine diacetate ma le aofaʻi o fua o le 16% ma le 32%.

Vaega:Nitrogen mama; piperidine; vailauga; lautele reagent; baloxacin vailauga; vailaʻau ogatotonu; Piperidine; Heterocyclic Compounds.

 

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O matou o Princechem Faletalavai fale gaosi pasi 20 tausaga poto masani. Ituaiga o vailaʻau tali atu i e etherification, ammoniation, chlorination, esterification, cyclization, hydrogenation ma Grignard tali atu, ma isi .. I le tuanaʻi 10 tausaga, sili atu nai lo 400 tusi oloa na atinaʻeina. I tausaga talu ai nei, sili atu nai lo 40 ituaiga o autu vailaʻau faufautua faufautua na atiaʻe, e aofia ai anti-kanesa, fatu fatu, digestive system, mafaufau faʻafitauli ma isi fanua. E aofia ai faʻatatau autu o API pei o Quetiapine, Fluvaxamine, Erlotinib, Gefitinib, Sunitinib, Lapatinib, Rabeprazole ma Lafutidine. Mo le tele o tausaga, o loʻo matou tuʻuina atu maualuga tulaga lelei vailaʻau faufautua mo le tele o lalolagi-lauiloa vailaʻau kamupani.

HI-Tech Enterprise na faʻamanuiaina i le YPC i le 2011. O le kamupani e tausisi i le faʻasaienisi ma tekonolosi fou ma e sili atu i le 10 faʻatulafonoina fatuga o mea fou.

O loʻo finau pea le YPC e faʻaaoga faiga faʻavaomalo faʻavaomalo faiga e faʻalauiloa ai a matou pulega ma faʻamautuina ai le faiga ole ISO9001: 2000, ISO14001: 2004 ma le OHS18001: 1999. I nai tausaga ua tuanaʻi, na pasi ai i luga o upega tafaʻilagi suʻesuʻega e sili atu i le 20 kamupani faʻavaomalo faʻavaomalo ma atunuʻu.

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